The antioxidant activity was tested using 2,2diphenyl1picrylhydrazyl, ferric ion reducing power assay, and phosphomolybdenum assay. Historically, aegle marmelos has been used for the number of ethonobotanical purposes. The tree is used in several cooking preparations in india. This is the first kind of report on the essential oil composition and in vitro antioxidant and anticancer activities of aegle marmelos l. Antidiabetic activity medicinal plant aegle marmelos linn. Phytochemistry and medicinal uses of the bael fruit aegle. The formula contains glycyrrhizia glabra rhizome part 200mg, aegle marmelos l. Antioxidant activity of leaf extract of aegle marmelos correa. Biological activities of crude extracts and chemical constituents of bael, aegle. Pharmacognostic standardisation and antiproliferative.
Aegle marmelos is used as ethno medicine against various human ailments. Phytochemical evaluation, antimicrobial activity, and. Aegle marmelos, antimicrobial activity, serial extracts, phytochemicals 687. Antidiabetic activity of leaf and callus extracts of aegle. In vitro anticancer activity on du145 and pc3 human prostate cancer cell lines was evaluated by 34, 5dimethyl thiazole2yl2, 5diphenyl tetrazolium bromide mtt assay. Pdf phytochemical evaluation, antimicrobial activity. Bael, vilwam, kuvalam, bengal quince, golden apple, stone apple and wood apple belonging to order sapindales and family rutaceae is a handsome deciduous aromatic tree growing upto 8. It is used to make juice, jam, syrup, jelly, toffee and other products. Aug 19, 2007 taxol is an important anticancer drug widely used in the clinic. Leaves, fruit, stem, bark of this plant is used because of its medicinal.
Phytochemical screening and estimation of total phenolic. Taxol, an anticancer drug produced by an endophytic fungus. This plant is having great potential to cure the disease like diabetes, cholesterol, peptic ulcer, inflammation, diarrhoea, and dysentery, anticancer. From the above results, dose dependent activity of the aqueous extract of the ripe fruits of aegle marmelos was observed.
It has a great mythological significance for hindus. The fungus was identified based on the morphology of the fungal culture and the characteristics of the spores. Phytochemical analysis on leaf extract of aegle marmelos correa. Anticancer activity research proved that extracts from aegle marmelos are able to inhibit the in vitro proliferation of human tumor cells, erythroleukemic hel, melanoma colo38, mdamb 231 and breast cancer mcf7 cell lines lampronti et al. While a lot of information is available about the antioxidant activity of fruit of a. Phytochemical analysis on leaf extract of aegle marmelos. Both aegle marmelos and moringa oleifera plant have great potential to treat diseases like antimicrobial, peptic ulcer, inflammation, anticancer, hepatoprotective, antioxidant, cardio. In the given study the drug was effective at a very low concentration of 1 mgml. Research article phytochemical evaluation, antimicrobial activity, and determination of bioactive components from leaves of. Aegle marmelos l currea inhibits the proliferation of transplanted ehrlich ascites carcinoma in mice. In this study, we investigated anticancer and antimicrobial activity of aegle marmelos leaf extracts and their chemical profile characterized by gas chromatography coupled mass spectrometry gcms. In this study the extract was tested using human cancer cell lines ht29 for its effects on cell viability, growth inhibition and cell morphology.
Leaf extracts of aegle marmelos are reported to have hy poglycemic and anticancer effects. The leaves, bark, roots, fruits and seeds are used extensively in the indian traditional system of medicine the ayurveda and in various folk medicine to treat myriad ailments. Rutaceae, commonly known as bael, bengal quince is a tree of indian origin, well known from pre historic time. New alkaloids from the leaves of aegle marmelos were reported viz. In vitro antioxidant and anticancer activity of leea indica. The bael aegle marmelos l corr is another indian plant, which has enormous traditional uses against various diseases. Nutritional value of aegle marmelos the fruit of a. The ability of the leaf extracts of aegle marmelosto inhibit growth of bacteria and fungi is an indication of its broad spectrum antimicrobial activity which could be a potential source for development of novel bioactive antimicrobial agents. Therefore it can be concluded that the aqueous extract of dried ripe fruit extract of aegle marmelos control group. Aegle marmelos has been used as antidiarrheal, antibacterial and antifungal agent in ayurveda and siddha system of medicine.
This fungus was grown in mid liquid medium and analyzed. Phytosomethe phytosome technology, developed by indena s. Taxol is an important anticancer drug widely used in the clinic. Siddha literatures were obtained from the library of unit of siddha medicine, university of jaffna. Sp joshiin vitro antiviral activity of bael aegle marmelos corr upon. In vitro study was found that the extract was comparable to that of ciprofloxacin and mostly active against the strains of vibrio cholerae, followed by escherichia coli e. The plant is highly used by the rural and tribal people for the treatment of diseases. Antimicrobial, antioxident and antidiabitic activity of. Pharmacognostic standardisation and antiproliferative activity of.
The stem bark of the plant has been reported to have anticancer activity 15. Pharmacognostic standardisation and antiproliferative activity of aegle marmelos l. Pdf biological activities of crude extracts and chemical. It grows well in the dry forests of hilly and plain areas.
Antigenotoxic activity of polyphenolic rich extracts from aegle marmelos l. Antibacterial and antioxidant activities of aegle marmelos. Tremendous pharmacological values of aegle marmelos. Aegle marmelos commonly known as bael is a plant indigenous to india. Aegle marmelos, phytochemicals, pharmacological properties. Utilization of bael in daytoday life has great nutritional, environmental as well as commercial importance. The extract is also useful in ophthalmia, deafness, inflammations, catarrh, diabetes, and asthmatic. Essential oil composition and biological activities of aegle. Antimicrobial and antioxidant activity of leaf extracts of. Nutritional and therapeutic potential of bael aegle marmelos. A mixture of boiled rice water and unripe fruit pulp cures vomiting during pregnancy by taking twice daily. Recently, series of phenylethyl cinnamides, which included new compounds named. Aegle marmelos, callus culture, methanolic extraction, antidiabetic activity introduction aegle marmelos l. Antioxidant, anticancer, antibacterial activities and gc ms analysis.
Research article phytochemical evaluation, antimicrobial. Antimicrobial activity was determined quantitatively by measuring inhibition zone around the disc impregnated with leaf extract over the lawn of bacterial. An endophytic fungus bartalinia robillardoides strain amb9 was isolated from aegle marmelos, a medicinal plant and screened for taxol production. Leaf extracts of aegle marmelos are reported to have hypoglycemic and anticancer effects. All the parts of this tree including stem, bark, root, leaves, fruit and seeds at all stages of maturity has medicinal virtues. Evaluation of antioxidant potential and phytochemical. The plant, though, being highly explored, still lacks sufficient evidences for the best variety possessing the highest degree of medicinal values. In colloquial terms they are known as bengal quince, indian quince, holy fruit, golden apple in english, and bael or bilva in hindi chemexcil, 1992, sharma et al.
Study of anthelmintic activity of aegle marmelos fruit. The other vernacular names are enlisted in table 1. The pulp is reported to contain water, sugar, protein, fiber, fat, calcium, phosphorus, potassium, iron and vitamins vit a, vit b, vit c and riboflavin. As a result, it has a high demand as alternative medicine for curing the diseases like diabetes, high cholesterol, peptic ulcer, inflammation, diarrhea and dysentery, constipation, respiratory infection. The extract prepared by boiling the bark, leaves or roots in water is useful as laxative, febrifuge, and expectorant. Biological activities and volatile constituents of aegle. Both aegle marmelos and moringa oleifera plant have great potential to treat diseases like antimicrobial, peptic ulcer, inflammation, anticancer, hepatoprotective, antioxidant, cardio protective. Although aqueous and other leaf extracts of aegle marmelos have been studied for anti ulcer activity, no reports.
The anticancer potential of folk medicine used in bangladeshi and used extracts of aegle marmelos for cytotoxic action using brine shrimp lethality assay. Evaluation of anti ulcer activity of ethanolic extract of. Evaluation of the antiinflammatory activity of aegle. Phytochemical and pharmacological screening of in vivo anti. Several crude extracts of this plants have been investigated and shown to have wide range of pharmacological effects. Aegle marmelos, a plant indigenous to india has been used by the inhabitants of the indian subcontinent for over 5000 years. Invitro anticancer activity of ethanolic extract of. Aegle marmelos, commonly known as bael and belonging to the family rutaceae is an important medicinal plant in the traditional indian system of medicine, the ayurveda. This article is from indian journal of pharmacology, volume 43. The stem bark of the plant has been reported to have anticancer activity. Aegle marmelos, antibacterial, anticancer, antidiabetic, antifungal, antihyperlipidaemic, antioxidant. Phytochemical evaluation, antimicrobial activity, and determination of bioactive components from leaves of aegle marmelos.
Chemotherapy has been the mainstay in cancer treatment for nearly 6 decades. Polyherbal formulations, extracts and the bioactives have. Antidiabetic activity of aegle marmelos and its relationship with its antioxidant properties. Utilization of bael fruit in daytoday life has a great nutritional, environmental as well as commercial importance.
Presence of phenolic compounds was identified in these extracts by qualitative analysis. In this study the extract was tested using human cancer cell lines ht29 for its effects on cell viability, growth inhibition and cell. The collected leaves were washed with running tap water and shade dried. Herbal medicine and medicinal plants have their roots deep embedded in our culture.
Bael is a slow growing, tough subtropical tree and is the only plant. Review article phytopharmacological properties of aegle. A leaf extract from the plant has been found to have insecticidal activity against the brown plant hopper, an important pest of rice plant in asia303. The collected information suggests that aegle marmelos has antidiarrheal activity. Biological activities and volatile constituents of aegle marmelos l. A study on development of herbal food product bael aegle. Antibacterial activity from leaves of aegle marmelos the ethyl acetate and methanol extracts prepare from leaves of aegle marmelos were tested for antibacterial activity and shown in table 1. Research article phytochemical evaluation, antimicrobial activity, and determination of bioactive components from leaves of aegle marmelos farinamujeeb,preetibajpai,andneelampathak department of biosciences, integral university, kursi road, lucknow, india correspondence should be addressed to neelam pathak. Bhavani 1pg and research department of biochemistry, adhiparasakthi college of arts and science, kalavai 632506, vellore district, tn, india article info abstract article history. Abstract aims and objectives the purpose of this study was to evaluate and compare the antiinflammatory activity of the aqueous root bark extract of aegle marmelos bilwa in experimental acute and chronic inflammatory animal models.
Phytosomes has nearly same antioxidant, antiproliferative and anticancer activity as that of methanolic extract of leaves of a. Aegle marmelos were kept in a beaker containing ml of %methanolcoveredwithpara lmandthenheatedat. The present study was designed to evaluate the invitro cytotoxicity activity of ethanolic extract of leaves of aegle marmelos in ht 29 human cancer cell lines. Phytochemical analysis and antioxidant property of aegle. Rutaceae is reported to be important plant in several ethnobotanical and ethnomedicinal studies for its antidiabetic, antiulcer, antiinflammatory, antipyretic, antioxidant and antimicrobial activity 44. It is present in sri lanka, tamilnadu, thailand, and malesia as a naturalized species. In vitro antioxidant and anticancer activity of leea. The present study was undertaken to study microscopic features of a. Aegle marmelos fruit pulp reported for the availability of steroids, terpenoids, flavonoids, phenolic compounds, lignin, fat and oil, inulin, proteins, carbohydrates, alkaloids, cardiac glycosides and flavonoids 20. Phytochemical analysis on leaf extract of aegle marmelos correa sonu singh, neeta singh abstract aegle marmelos is a subtropical plant which can grow up to an altitude of 1200 m from the sea level. Aegle marmelos extract effectively reduced the oxidative stress induced by alloxan and produced a reduction in blood sugar. Uses, side effects, interactions, dosage, and warning. The extract of aegle marmelos was found to exhibited toxicity on.
Pdf phytochemical evaluation, antimicrobial activity, and. Antioxidant activity of leaf extract of aegle marmelos correa ex roxb. Utilization of bael in daytoday life has great nutritional, environmental as well as. A number of chemical constituents and various therapeutic effects of a. The medicinal value of bael fruit is very high when the harvests just begin to ripen. Nadhiya and vadivazhagi antioxidant and phytochemical properties of combination international research journal of pharmaceutical and biosciences irjpbs 2015. Aegle marmelos or bael is a middle sized slender aromatic armed tree native to india and pakistan. Aegle marmelos, antibacterial, anticancer, antidiabetic, antifungal. Biological activities of crude extracts and chemical. Bael sharad sankhe1, madhuri jangda2 1, 2 chemistry research lab,patkar varde college,goregaonw62 abstract.
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